DeSoto House Hotel
Stay the night at the DeSoto House Hotel on Galena’s Main Street, which dates back to 1855 and is Illinois’ oldest operating hotel. The DeSoto has hosted such notable guests as Abraham Lincoln (who spoke from a hotel balcony to the assembled crowd below) and served as the presidential campaign headquarters for Ulysses S. Grant. The hotel features 55 Victorian-style guest rooms, three restaurants and boutiques.












