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Shedd Aquarium

Main Street Inn

404 S. Main St., Galena, IL 61036

Vacation Rentals

Located on Galena's historic downtown Main Street, the Main Street Inn is a cozy, inviting place to relax that is listed on the National Register of Historic Places (circa 1850).

Main Street Inn offers 6 luxurious and spacious rooms located on the 2nd floor that will meet the needs of romantic adventures, friend getaways, or anything in between. Walk out the front door to take a stroll up Main Street and browse through Galena's unique stores and boutiques, enjoy dining at one of Galena's fine restaurants, or stop by one of our wine shops. Or stay in and simply enjoy the comforts of your room.

Whatever your reason for coming to Galena, the Main Street Inn is here for you!

What's happening nearby...

Snowflakes and Sweets Stroll

Galena's Main Street •  Dec 20 @ 12noon

Galena is hosting Snowflakes and Sweets Stroll 2025!

Read more about Snowflakes and Sweets Stroll

General Grant's Home Front Reenactment & Encampment

Depot Park  •  Apr 25 – Apr 26 @ 9AM

Experience life in the 1860s through a Living History Encampment and Civil War Battle.

Read more about General Grant's Home Front Reenactment & Encampment

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